• From this page You could reach all the figures at the Turkish Journal of Hematology archive.
  • You could save all the imges by the save as button and paste them to  office documents.
  • Please use the articles details for reference.
  • You could see the abstracts of the images from the link above the image.




“Niche” concept and the hematopoietic stem cell niches
A stem cell niche is defined as the most suitable tissue microenvironment where somatic cells (parent cells) or in some cases extracellular matrix elements and stem cells are present in an exclusive interaction. In recent years, promising data were published revealing the molecular and functional significance of cell-cell contacts in stem cell proliferation (self-renewal) and differentiation into mature cells. In this brief review, recent progress has been documented with special emphasis on the structural-functional relationship between stem cells and surrounding cells. Hematopoietic stem cells and their niches are among the most studied stem cell types and cell-cell interactions, which have specific as well as some common properties observed in other niche sites in the human body. Some of the signaling pathways, which are illustrated by original drawings herein, obviously play major roles in stem cell self-renewal capacity and differentiation status. Therefore, stem cell niches stand as the most critical biological sites in stem cell physiology and could also be considered as the new targets for the treatment of certain diseases.

addictive behavior

adolescent compulsive gambling gambling click here to see if you are a compulsive online trader

addictive behavior

adolescent compulsive gambling gambling click here to see if you are a compulsive online trader

addictive behavior

adolescent compulsive gambling http://www.800gambler.org/ click here to see if you are a compulsive online trader

addictive behavior

adolescent compulsive gambling gambling help click here to see if you are a compulsive online trader

addictive behavior

adolescent compulsive gambling gambling problem click here to see if you are a compulsive online trader

buy biaxin without prescription

buy biaxin online buy clarithromycin buy biaxin

buy biaxin without prescription

buy biaxin online http://www.geospatialworld.net/Event/View.aspx?EID=53 buy biaxin

buy biaxin without prescription

buy biaxin online buy clarithromycin buy biaxin

buy biaxin without prescription

buy biaxin online buy biaxin 250mg buy biaxin

buy biaxin without prescription

buy biaxin online buy biaxin 250mg buy biaxin

cheapest clarithromycin

order biaxin 500mg buy clarithromycin buy clarithromycin

cheapest clarithromycin

order biaxin 500mg buy clarithromycin buy clarithromycin

cheapest clarithromycin

order biaxin 500mg http://www.geospatialworld.net/Event/View.aspx?EID=43 buy clarithromycin

cheapest clarithromycin

order biaxin 500mg http://www.geospatialworld.net/Event/View.aspx?EID=43 buy clarithromycin

cheapest clarithromycin

order biaxin 500mg http://www.geospatialworld.net/Event/View.aspx?EID=43 buy clarithromycin

buy abortion pill online

cytotec abortion pill buy online i need to buy the abortion pill buy abortion pill online

buy abortion pill online

cytotec abortion pill buy online abortion pill buy abortion pill online

buy abortion pill online

cytotec abortion pill buy online abortion pills buy abortion pill online

buy abortion pill online

cytotec abortion pill buy online http://sagesoftware.co.in/Default.aspx buy abortion pill online

buy abortion pill online

cytotec abortion pill buy online i need to buy the abortion pill buy abortion pill online

abortion pill prescription

abortion pill buy online abortion pill cytotec abortion

abortion pill prescription

abortion pill buy online abortion pill cytotec abortion

abortion pill prescription

abortion pill buy online abortion pill cytotec abortion

abortion pill prescription

abortion pill buy online abortion pill cytotec abortion

abortion pill prescription

abortion pill buy online http://www.cengage.co.in/content/about-us cytotec abortion

mail order viagra without prescription

buy viagra online a href female viagra alternative viagra for sale without a prescription

mail order viagra without prescription

buy viagra online a href viagra online viagra for sale without a prescription

mail order viagra without prescription

buy viagra online a href viagra online viagra for sale without a prescription

mail order viagra without prescription

buy viagra online a href http://www.cengage.co.in/content/privacy-statement viagra for sale without a prescription

mail order viagra without prescription

buy viagra online a href viagra online viagra for sale without a prescription

kamagra without prescription

photos kamagra kamagra herbal kamagra alternative

kamagra without prescription

photos kamagra europe online sale kamagra herbal kamagra alternative

kamagra without prescription

photos kamagra kamagra herbal kamagra alternative

kamagra without prescription

photos kamagra europe online sale kamagra herbal kamagra alternative

kamagra without prescription

photos kamagra how to use kamagra herbal kamagra alternative

herbal kamagra jelly alternative

kamagra jelly pharmacy buy kamagra jelly online safe free kamagra jelly

herbal kamagra jelly alternative

kamagra jelly pharmacy kamagra jelly free kamagra jelly

herbal kamagra jelly alternative

kamagra jelly pharmacy http://www.cengage.co.in/content/copyright-notice free kamagra jelly

herbal kamagra jelly alternative

kamagra jelly pharmacy kamagra jelly free kamagra jelly

herbal kamagra jelly alternative

kamagra jelly pharmacy http://www.cengage.co.in/content/copyright-notice free kamagra jelly

amoxicillin uk

mail order amoxil generic amoxil amoxil prescription buy

amoxicillin uk

mail order amoxil buy amoxicillin online a href amoxil prescription buy

amoxicillin uk

mail order amoxil buy amoxicillin online a href amoxil prescription buy

amoxicillin uk

mail order amoxil get amoxicillin amoxil prescription buy

amoxicillin uk

mail order amoxil buy amoxil online amoxil prescription buy

natural synthroid

synthroid prescription buy http://www.cengage.co.in/content/english-language-teaching where to buy thyroxine online

natural synthroid

synthroid prescription buy http://www.cengage.co.in/content/english-language-teaching where to buy thyroxine online

natural synthroid

synthroid prescription buy natural synthroid where to buy thyroxine online

natural synthroid

synthroid prescription buy synthroid where to buy thyroxine online

natural synthroid

synthroid prescription buy http://www.cengage.co.in/content/english-language-teaching where to buy thyroxine online

female herbal laxative

order laxative online http://www.cengage.co.in/content/library-reference get bisacodyl

female herbal laxative

order laxative online order laxative online get bisacodyl

female herbal laxative

order laxative online laxative get bisacodyl

female herbal laxative

order laxative online http://www.cengage.co.in/content/library-reference get bisacodyl

female herbal laxative

order laxative online laxative without prescription get bisacodyl

ampicillin prescription buy

buy principen in great britain http://www.cengage.co.in/content/competitive-examinations photos ampicillin

ampicillin prescription buy

buy principen in great britain mail order principen photos ampicillin

ampicillin prescription buy

buy principen in great britain ampicillin photos ampicillin

ampicillin prescription buy

buy principen in great britain get ampicillin photos ampicillin

ampicillin prescription buy

buy principen in great britain http://www.cengage.co.in/content/competitive-examinations photos ampicillin

buy biaxin 500mg

biaxin reviews ordering biaxin purchase biaxin

buy biaxin 500mg

biaxin reviews clarithromycin purchase biaxin

buy biaxin 500mg

biaxin reviews clarithromycin purchase biaxin

buy biaxin 500mg

biaxin reviews clarithromycin buy purchase biaxin

buy biaxin 500mg

biaxin reviews clarithromycin purchase biaxin

purchase cipro online

get ciprofloxacin order cipro cheap ciprofloxacin

purchase cipro online

get ciprofloxacin ciprofloxacin cheap ciprofloxacin

purchase cipro online

get ciprofloxacin ciprofloxacin cheap ciprofloxacin

purchase cipro online

get ciprofloxacin ciprofloxacin cheap ciprofloxacin

purchase cipro online

get ciprofloxacin ciprofloxacin cheap ciprofloxacin

cleocin online shop in uk

get clindamycin avoid prescription http://www.geospatialworld.net/Event/View.aspx?EID=62 cleocin online

cleocin online shop in uk

get clindamycin avoid prescription clindamycin cleocin online

cleocin online shop in uk

get clindamycin avoid prescription order cleocin online cleocin online

cleocin online shop in uk

get clindamycin avoid prescription http://www.geospatialworld.net/Event/View.aspx?EID=62 cleocin online

cleocin online shop in uk

get clindamycin avoid prescription order cleocin online cleocin online

order dexone

female herbal dexone get discount dexone online alternative to dexamethasone

order dexone

female herbal dexone dexamethasone dosage alternative to dexamethasone

order dexone

female herbal dexone dexamethasone alternative to dexamethasone

order dexone

female herbal dexone dexamethasone alternative to dexamethasone

order dexone

female herbal dexone dexamethasone alternative to dexamethasone

natural duricef

natural Cefadroxil get discount duricef online female free sample Cefadroxil

natural duricef

natural Cefadroxil http://www.geospatialworld.net/Event/View.aspx?EID=105 female free sample Cefadroxil

natural duricef

natural Cefadroxil cefadroxil female free sample Cefadroxil

natural duricef

natural Cefadroxil cefadroxil female free sample Cefadroxil

natural duricef

natural Cefadroxil cefadroxil female free sample Cefadroxil

order vantin

natural vantin cefpodoxime samples vantin prescription buy

order vantin

natural vantin cefpodoxime vantin prescription buy

order vantin

natural vantin generic vantin online vantin prescription buy

order vantin

natural vantin http://www.geospatialworld.net/Event/View.aspx?EID=151 vantin prescription buy

order vantin

natural vantin generic vantin online vantin prescription buy

generic ceftin

buy ceftin online a href cefuroxime buy ceftin online safe

generic ceftin

buy ceftin online a href cefuroxime buy ceftin online safe

generic ceftin

buy ceftin online a href buy cheap ceftin online uk buy ceftin online safe

generic ceftin

buy ceftin online a href http://www.geospatialworld.net/Event/View.aspx?EID=154 buy ceftin online safe

generic ceftin

buy ceftin online a href order cefuroxime online buy ceftin online safe

abortion pill buy online

where can i buy abortion pills abortion pill order abortion pill

abortion pill buy online

where can i buy abortion pills abortion pill order abortion pill

abortion pill buy online

where can i buy abortion pills http://ateneobergamo.it/schedaNews.aspx?id=216 order abortion pill

abortion pill buy online

where can i buy abortion pills abortion pill order abortion pill

abortion pill buy online

where can i buy abortion pills abortion pill order abortion pill

keflex without prescription

buy keflex online cephalexin get keflex online

keflex without prescription

buy keflex online alternative to cephalexin get keflex online

keflex without prescription

buy keflex online http://www.fareastjournals.com/conf_detail.aspx?conf_id=5 get keflex online

keflex without prescription

buy keflex online http://www.fareastjournals.com/conf_detail.aspx?conf_id=5 get keflex online

keflex without prescription

buy keflex online women does cephalexin work get keflex online

how does chloromycetin work

how to use chloramphenicol generic chloromycetin online order chloromycetin online

how does chloromycetin work

how to use chloramphenicol chloramphenicol order chloromycetin online

how does chloromycetin work

how to use chloramphenicol http://www.fareastjournals.com/conf_detail.aspx?conf_id=6 order chloromycetin online

how does chloromycetin work

how to use chloramphenicol http://www.fareastjournals.com/conf_detail.aspx?conf_id=6 order chloromycetin online

how does chloromycetin work

how to use chloramphenicol http://www.fareastjournals.com/conf_detail.aspx?conf_id=6 order chloromycetin online

abortion pills

where can you buy the abortion pill http://www.fareastjournals.com/journal_detail.aspx?jid=18 pill for abortion online

abortion pills

where can you buy the abortion pill pill for abortion online pill for abortion online

abortion pills

where can you buy the abortion pill abortion pill pill for abortion online

abortion pills

where can you buy the abortion pill pill for abortion online pill for abortion online

abortion pills

where can you buy the abortion pill abortion pill pill for abortion online

buy augmentin online

how to use augmentin http://www.fareastjournals.com/journal_detail.aspx?jid=22 female free sample augmentin

buy augmentin online

how to use augmentin augmentin female free sample augmentin

buy augmentin online

how to use augmentin augmentin female free sample augmentin

buy augmentin online

how to use augmentin how does augmentin work female free sample augmentin

buy augmentin online

how to use augmentin clavulanate dosage female free sample augmentin

Authors: Alp Can

Keywords: Hematopoetik kök hücreleri, kök hücresi, niş, Notch sinyali, Wnt sinyali

  • Year: 2007
  • Number: 3
  • Referance No: 85856
  • Figure 1. Two types of niches are defined depending on the existence of parent cells adjacent to stem cell(s). A. Multicellular niche is typically composed of two or more types of parent cells interrelated with each other and with stem cells (arrows). They build several intercellular adhesion sites and molecular signaling pathways providing a suitable niche environment. B. Acellular (extracellular matrix) niche is characterized as the expression of certain cell adhesion molecules on the stem cell surface which interact with specific extracellular matrix proteins (arrows). ECM: Extracellular matrix (original drawing by A. Can).
  • Figure 2. N-cadherin (+) cell adhesion sites (small rectangle between osteoblast and hematopoietic stem cell, HSC) stimulate the Wnt/ß-catenin signaling pathway, which induces HSC proliferation while significantly inhibiting their differentiation, thereby resulting in functional selfrenewal (Original drawing by A. Can).
  • Figure 3. Notch signaling executed by a series of highly conserved receptors is a key factor in inhibiting differentiation. Intact Notch signaling is required for Wnt-mediated maintenance of undifferentiated HSCs. Notch signaling is active in HSCs and downregulated as HSCs differentiate. Inhibition of Notch signaling leads to accelerated differentiation of HSCs (Original drawing by A. Can).

Copyright © 2024 Atlas of Hematology. All rights reserved.